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Niger J Physiol Sci ; 35(1): 10-19, 2020 06 30.
Artículo en Inglés | MEDLINE | ID: covidwho-882015

RESUMEN

Coronavirus Disease 2019 is a wide-spreading severe viral disease caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) virus that needs to be urgently eradicated. SARS-COV-2 has infected millions of people worldwide and results in more than three hundred thousand deaths. Several repurposed drugs have failed to successfully eradicate the infection. Multiorgan failure caused by pronounced inflammation and systemic coagulation accounts for severe complications and death associated with diseases. Bromelain appears to be a potential candidate that may be used to inhibit or prevent the symptoms of the diseases. Its anti-inflammatory and anticoagulatory properties make it a potential agent that may slow the progression of the disease. In this review, we highlighted the beneficial effects of bromelain based on both experimental and clinical evidence that make bromelain a good candidate for the treatment of symptoms of CoVID-19 infection.


Asunto(s)
Bromelaínas/uso terapéutico , Infecciones por Coronavirus/tratamiento farmacológico , Fitoterapia , Neumonía Viral/tratamiento farmacológico , Ananas , Betacoronavirus/ultraestructura , Bromelaínas/farmacología , COVID-19 , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/inmunología , Infecciones por Coronavirus/virología , Interacciones Huésped-Patógeno , Humanos , Pandemias , Extractos Vegetales/farmacología , Extractos Vegetales/uso terapéutico , Neumonía Viral/epidemiología , Neumonía Viral/inmunología , Neumonía Viral/virología , SARS-CoV-2 , Tratamiento Farmacológico de COVID-19
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